Biokof 

Butamirate Citrate 

INN 7.5 mg/ 5 ml 

COMPOSITION

• Biokof 100 ml syrup: Each 5 ml Biokof syrup contains Butamirate Citrate INN 7.5 mg.

DESCRIPTIONS

Butamirate Citrate acts directly on the brain's cough center to suppress cough. It is safe and non-sedating. Butamirate Citrate is rapidly and completely absorbed after oral administration. Butamirate Citrate is extremely protein-bound and plasma elimination half-life is about 13 hours. The active metabolites of Biokof have also antitussive action.

INDICATION

Butamirate Citrate is used to relieve dry (non-productive) cough. Butamirate Citrate is also used for pre- & post-operative cough sedation in patients who will undergo surgical procedures and bronchoscopy. It can be used in the acute cough of any etiology, whooping cough, and cough due to acute lower respiratory tract infections (tracheitis, laryngitis, bronchitis, etc.). 

DOSAGE AND ADMINISTRATION

• Children (3-6 years): 5 ml 3 times daily.
• Children (6-12 years): 10 ml 3 times daily.
• Adolescent (age over 12 years): 15 ml 3 times daily.
• Adults: 15 ml 4 times daily.

USE IN PREGNANCY AND LACTATION

• Butamirate Citrate should not be used during the first three months of pregnancy. During the rest of pregnancy, it can be used if indicated by a physician but with caution.

CONTRAINDICATION

• Hypersensitivity to the active ingredient.

WARNING & PRECAUTION

• Due to the inhibition of the cough reflex by Butamirate Citrate, the simultaneous administration of expectorants has to be avoided, because it may lead to the stagnation of mucus in the respiratory tract, which increases the risk of bronchospasm and airway infection.

SIDE EFFECT

• Tolerance of Butamirate Citrate is good. Adverse reactions such as rash, nausea, diarrhea, and vertigo have been observed in a few rare cases, resolving after dose reduction or treatment withdrawal.

OVERDOSE

• Overdose may cause nausea, vomiting, diarrhea, dizziness, and hypotension. The usual emergency assistance should be taken: activated charcoal, saline laxative & symptomatic treatment should be given.

STORAGE

• Keep away from light and moisture stored below 30°C. Keep all the medicines out of the reach of children.

COMMERCIAL PACK

• Biokof 100 ml Syrup: Each amber color glass bottle contains 100 ml syrup.

Biopharma Ltd. Produces BIOKOF 100 ML SYRUP it is a trusted product for alleviating various discomforts, and it's commonly found in pharmacies and stores.